Lentiviral vectors have demonstrated great potential as gene therapy vectors mediating efficient in vitro and in vivo gene delivery and long-term transgene expression in both dividing and nondividing cells. They have the advantages of a large cloning capacity, the lack of a requirement for viral gene expression, and the capacity to integrate into the target cell genome for stable transduction.
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Oncolytic Virus
General FictionOncolytic viruses (OVs) are a class of viruses that can selectively replicate in and lyse cancer cells, and subsequent spread with a tumor while not causing damage to normal cells. Besides the direct oncolytic activity, OVs are also effective in sti...