When seventeen year-old Runner was sentenced to death for stealing a loaf of bread in MegaCity One, his dreams were literally at an end. But then he opts to sign up for the Remnants of Men, a government sanctioned search for a rumoured fresh water lake beyond a radiated wasteland. At first, it seemed like a second chance to a new life, the transformation from zero to hero. But after an encounter with a rabid gang of men suffering an acute insanity, he soon comes to understand that he is one of many discarded into the wasteland to study the cannibalistic effects of a new drug called the Sixth Sense. Olivia Patterson has had one too many doses of the Sixth Sense and owes a massive debt to a shadowy rebel and loan shark called Death-Throe. Being the daughter of the City's dictator, she knows too well that the gallows awaits any who associates with the rebel. In an attempt to free herself, she acquires an asset in the form of Runner and finds herself always at the edge, for if he survives it means freedom for both, but if he dies...

Sherlock Holmes has a case. But this is not any ordinary case. Evanna Holmes is the intellectual visitor and she informs him of a murder, the murder of her mother Alia Holmes- Sherlock's unknown older sister. But once Sherlock and his trusty companion Dr John Watson agree to investigate it plummets them all into a dangerous world of secrets and mystery.