The children of the original Sky High group start their first day of high school at Sky High, a school meant for teens to learn about and better control their powers. Their parents of course admitted them once they became of age, and most of their parents are busy with hero work as well. They experience their new school lives filled with familiar teachers, unusual powers, and eccentric students. Going through high school is not easy especially with powers and an ongoing investigation. Will the group be able to survive high school and get through this mystery?