Will's sister Pamela has powers like Spider-Man. When she was 5 the same thing happened to her how Peter was bite by the spider. Now she's in high school with her brother and best friend and has to do power placement.

Kathrine Stronghold had a lot to live up to. Her mom and dad were the most famous super heroes around after all. When she gains powers that neither of her parents have what happens?

Ava Stronghold is the adopted daughter of Steven and Josie Stronghold and adopted sister of Will with the ability to shift into a dragon. When she starts attending Sky High for the first time, everything Ava knows starts getting dramatic as she recieves attention from a certain misunderstood bad boy.

Madeline(aka Maddie) is the daughter of the Commander and Jetstream, two famous superheroes. Her brother Will, neighbor Layla, and herself are starting high school. However, this high school isn't just an ordinary high school, its a floating high school for heroes in training.