In the silent reaches of space, the Silent Nebula-a force that feeds on "empty noise" and emotional numbness-has begun stealing the "Heart Melodies" of Earth's inhabitants. When a person's melody is stolen, they become indifferent and lose their passion. To save the harmony of the universe, the Fairy Prince from the Planet Symphony arrives on Earth to find the legendary Star Conductors-the PreCure.

Kazama Meiko, a 14- year old girl discovers a party invitation in her room. On the way to the party, she finds a girl called Precure fighting for justice. She then knows that the one who sent the letter was the girl named Kiriya Minako/ Cure Pop stating that she needs a partner to fight with her because their world is in grave danger. Will they be able to protect the world as Precure?