10 year old Misaki, escape the murderers of her mother, that got killed nearly 5 years ago. After a long walk she encounters a large gate, where two men try to capture her but is saved by a 'perverted prince' known as Nayumi, who is a teacher at Alice Acedemy, she unexpectedly enrolls to the alice academy as Nayumi senses she has an alice which hasn't awakened yet. She encounters Natsume and soon meets Mikan, Ruka and Hotaru. Misaki's Alice's are Angel Possession and Water alice.