Loraine, "the greatest martyr of all" ang dakilang kakambal ni Elaine na sumalo lahat ng mga nagawang gusot nito at ang inakala nilang pakawala, rebelde at masamang babae. Ivan; "the ultimate sweet and caring hunk" but when he fell in love. ito na mismo ang lumalayo at nang-iiwan sa babae. What if the playful destiny placed them in a situation, the two will be living in one roof for atleast 100 days. Ano kaya ang mga pwedeng mangyari? Is there a possibility that a simple YOU AND I will become YOU AND I FOREVER?