More than 60 years ago, a virus broke out, causing people to become insane. The world was nearly destroyed. Then a group of Scientists created 25 communities, each one with a facility to study and cure Infected. It was contained and being treated, until now. Someone, or something, let Infected out of all facilities, and broke the world into madness once again Marriane, Andrew, and many more, adjust to the harsh environment of the outside world, and try to find out who had Spread the virus once again.