When world-renowned surgeon Persephone Voss (OC) joins Seattle Grace, she brings centuries of secrets, immortal children, and a flair for the dramatic. As she navigates hospital politics, family chaos, and a growing connection with Addison Montgomery, her carefully kept supernatural world begins to unravel.

Isla robbins is the little sister of Arizona robbins. She is just as bubbly as her sister. Isla like her sister takes an interest in peds. Isla tries to be there for Alex as he learns that izzie has cancer But things change between the two of them. She wants to be there for him but he is hurt and soon confines in them as they start hooking up {OC/Alex Karev} {Season 5 onwards}

Bella Montgomery is the daughter of Addison Montgomery. Back in New York things were different. She was with mark and she was on love with him and they were happy. Or so she thought. Bella was heartbroken when she learnt that mark had cheated on her and not just with anyone but with her own mother Bella and Derek hooked up afterwards as she went to Seattle with him as she started her internship. Bella and Derek continue to hook up in Seattle but with it being sex can they keep it that way knowing just how complicated that Their past is and how they have been hurt before?

Esme robbins is the younger sister of Arizona robbins and is also a surgical resident at Seattle grace hospital. Esme is one of the best in her class. When the merger of Mercy west hospital happens. It brings a load of new surgeons along including Jackson Avery. Esme doesn't have the best first impression of Jackson. She thinks he is cocky and full of himself. She doesn't trust him. Before long, Esme and Jackson are becoming friends much to the horror of the Seattle grace and mercy west surgeons. Esme and Jackson soon get closer than they should as they start to sleep together. They claim it's nothing both of them wanting to focus on their careers but for long could they deny how they are feeling for each other even if it means them both seeing other people and lying to themselves and will they admit what they truly want even with disasters happening around them

Chloe Torres is the younger sister of Callie Torres. She is a surgical resident at Seattle grace hospital. Mark Sloan is best friends with Callie. He has a complicated relationship with her. They sleep together on and off but when Callie sees how close that mark is getting to her sister. She warns mark to stay away. Mark finds this hard, he is a man whore but he knew that he never looked at Chloe like that and it starts to change how he is looking at Chloe. Mark tries his best to stay away from Chloe for his friendship with Callie but it is only so long wrote he mad Chloe end up close and they end up in bed but can they keep what they have secret or will others find Out and will Chloe be the girl that changing mcsteamy into more than a man whore? And how long would it be before Callie finds out the truth?