Detective Jay Halstead has some family problems to deal with, his sister and her husband abandoned there daughter Charlie at Chicago Med, will Jay be able to convince Charlie this wasn't her fault.

When Alex Halstead finally gets reunited with her brothers after 10 years of being separated from each other How is Jay and Will gonna react when their lost sister suddenly gets brought in to the ED of Chicago Med?

During a raid the team stumbles upon a young girl, the girl quickly becomes attached to Hank. How will Hank respond? Hank's world gets shaken up and changed.