Lena Luthor is just moving to National City, a year into Kara being Supergirl, however the difference on this earth, Earth-623, is that Lena Luthor is moving to National City with her 3-year-old daughter Loretta "Lori" Luthor. Lena having a daughter will then completely change Kara and Lena's story as we know it, as well as their relationships with people around them.