A year after the events of kill la kill Ryuko and everyone else have moved on and Ryuko lives with her older sister Satsuki and is attending normal high school. Despite no longer possessing senketsu Ryuko is still the same fighter she's always been and gets into all sorts of trouble and adventure. One day Ryuko comes across a boy named Y/N who brings about a new adventure.

Meet (Y/N), the most powerful hero on earth... that no one has ever heard of. He's done it all, slay monsters, avert disasters, and save the planet and if there is one thing he's learned is that he REALLY wants a break. After deciding to have a normal life, (Y/N) has chosen to finish high school. And what better place to have a normal school life than Honnouji Academy!!!! Anywhere... Literally anywhere else.

Ryuko found a strange area in her father's basement, and summons a strange boy from an alternate place in reality.