Many people didn't believe the destruction of the earth would arrive. And no one was prepared when the entire universe was engulfed in a sick plague inflicted by the incurable bacteria, Reighbulance. Reighbulance transforms people into blood-thirsty killers, called Reighs, that eat human flesh. Now, after half the population is dead, those still alive and uninfected are fighting in an apocalypse for their lives against the Reighs, those infected by the bacteria. But one thing is becoming painfully clear; the uninfected aren't wining. . .

Jessica and her friends sophiee, frank, billy, Jacob and Alex all have an unexpected visit by Madeline the un-wanted ghost girl, this girl is different she just wants help but people keep running, until there's Jessica. Jess gets into hospital and when they plaster up her arm and keep her for over night observation, something in the hospital goes horribly wrong. Everyone in the hospital is evacuated to another hospital close by due to machine failures and black outs in a storm, but when they forget that Jess and her friends are in the last room in the building and lock the place down, there is no way out.