This is the story of Diane (Alex Gonzaga), an optimistic rich girl who seems to have everything; and Ysabel (Yen Santos), an average working girl who led a rather 'lifeless' life since her boyfriend died. One day, because of an accident, Diane and Ysabel's fates became entwined. In her state of coma, Diane discovered through the mysterious "Scheduler" (Matt Evans) that she was not destined to die yet. Then she will be given a second chance at life, that is, after completing a special task-to gather three "pure" teardrops shed out of true love by three people outside her family within the next 40 days. To help her accomplish her task, Scheduler gives Diane the chance to inhabit the body of Ysabel. Will Dianne and Ysabel succeed in bringing their lives back after the 40-day ordeal fate has put them through?

Si Girl - may pagka-childish, slowpoke, exaggerated mag-isip, accident prone, sweet, mabait, super friendly, hindi nauubusan ng energy, positive thinker pag dating sa mga problema. Si Guy - mature, seryoso, hindi ngumingiti, bossy, masungit, snob, magaling mag-handle ng mga bagay, a perfect decision maker, hindi nakikipag-kaibigan, lahat tinuturing nyang competitors/kaaway. What if magtagpo ang landas nilang dalawa? At magkaroon ng biglaang kasal dahil sa di inaasahang pangyayari? Are they going to prove na total opposite attracts? O maghihiwalay din sila in the end? paano pakikisamahan ni girl ang asawa nyang mafia boss? matagalan kaya ng isang mafia boss ang asawa nyang slow? Let's see..