Wade Wilson attempts suicide(again) only to be stopped by a man in a mask. This man was Spider-Man who heroically saves him and inspires him to use his Immortality for decent reasons.

Peter, mourning over the death of his late girlfriend, Mary-Jane Watson, meets the ever-notorious Merc with a Mouth, Wade Wilson, a.k.a Deadpool. Deadpool is a man who's always known what he wants, and he wants the shy, skittish, goody-two-shoes Peter Parker, a.k.a Spiderman. Deadpool unlocks a part of Peter that had been kept buried and hidden, and it scares the hell out of him. Will he accept Deadpool and let loose that side of him? Join the fun and wisecracks as Deadpool takes Spiderman for a crazy, wild ride that Peter's not sure he's ready to handle.