When it is discovered that some of the most threatening forces in not only the world- but universe, and perhaps even other realms- are working together, the Winchester brothers team up with a high functioning sociopath/ex-army doctor duo, a madman with a blue box and a particularly strange interest in fezzes, and a girl with no direct past, present, or future in an adventure that will tie everything together in ways never imagined.

The Doctor and Clara decide to try a new thing, visiting a crime scene. Their paths cross the consulting detectives, John Watson and Sherlock Holmes. The Doctor decides to take Sherlock and John along in the TARDIS, and end up in Kansas in the USA crossing the Winchesters. What will they find in this adventure?