At a very young age, Gino Romualdez suffered from a heart disease which caused him to be very careful for his life. All of his dreams were slowly crashing down, all of his plans for himself and for her Ate Sabrina, disappeared. He felt everything he ever wanted was taken away from him all at once. But Vanilla Mallari, never allowed that to happen. For her first love, she is willing to do everything. She's willing to take all the pain away for the sake of his happiness. For years, he convinced himself that he will survive, that he will live for he doesn't want to leave the people he loves. But fate's really unfair, after all the struggles one thing's for sure; Gino is willing to do everything, whatever it takes; for he doesn't want to make his dreams just be dreams. Knowing that he'll die soon, he made all the memories he can make for he won't be forgotten fast. But she never liked the idea. For she will do everything--all for love 'cause she believes that she is the only way. She's his medicine. She's his cure.

Sabi nila.."First Love Never Dies, even if you have found a new love, the sweet memory of the past will continue to haunt you for the rest of your life." Jhyd Madrigal was Irah's First Love. They've been together for almost 3 years, at Maraming nagsasabi na they are really a "perfect couple." but then suddenly, nagbago ang lahat dahil lamang sa isang maling akala. Irah broke up with Jhyd at nagdecide siyang lumayo nalang para makalimutan ang lalaking unang nagpatibok ng puso niya, lumayo para makapagsimula ng panibagong buhay at para makahanap ng bagong lalaking magmamahal sa kanya. ngunit, sa kanyang paglayo ba ay makakanahap siya ng bagong mamahalin at tuluyan na niyang makakalimutan ang kanyang First Love? paano kung bumalik ito.. will she give him a chance?