When Sam and Dean Winchester's father disappears, they follow his last known places which leads them to come across new yet familiar faces. Alice Colt is a descendant of Samuel Colt and now currently the Colt Heir, meant to wield the weapon, Peacemaker and break the Colt Curse that has haunted her family for years. By her side is her son, Jamie Colt who she is focused on giving him the opportunity to live a normal and stable, something she lacked. Yet Jamie wishes to be involved in his family's legacy and to become what the Colts were - heroes and protectors. With the curse looming over the Colts and the brothers determined to find their father, they all agree to help each other out. The four band together which leads them to deal with the supernatural and problems that seem to only lead to more problems. The group continue to figure out where the road will lead them and how it will end, for better or for worse.