The minute Wyatt stepped into the manse, something was off. In fact, a lot of things seemed to raise red flags. For example: The guests all had an unusual talent. There was a mentally insane host who seemed serious enough when he told them to murder each other. An unhealthy amount of deadly rooms were located within the manse. The little boy who visited them occasionally seemed too insane to be innocent. Did something happen before they were trapped in the manse? The ambience of despair tests each guest to the limits of their abilities and sanity as they continue to play the twisted game. Will Wyatt and the fifteen other "guests" find out the truth about the killing game, or will they perish before any of the mysteries are revealed?

While Marine and the others were fighting in Hope's Peak Academy, Shane and a group of 15 students are trapped on an chain of islands by none other than himself, Monokuma. Why did the school send them there? What is going on? Shane must find out before all of his friends fall into despair. A sequel to DanganRonpa- The Despair of My Life