Meet Sherlock Holmes- a 15 year old sociopath; arrogant, tactless, rejected, but enjoys a life of solitude and deducing. Meet John Watson- a 15 year old footballer; quiet, popular, caring, but endures a life of isolation and oppression. A transfer from a state school, John pushes open the door of Room 22 to find the most crucial part of his life he never knew existed; a teenage boy with the mind of a philosopher, who just so happens to be able to precisely analyse every detail of John's life, whilst being able to piss everyone else off at the exact same time.

Sherlock Holmes was dying. His body slowly beginning to break down. ... John Watson was an aspiring writer, but with a dark past. ... "It's always the unexpected that change our lives." Sherlock Holmes has always had a problem with illness ever since he was diagnosed with cancer when he was seven. After many years have passed Sherlock is now cancer-free and it isn't soon before he bumps into a man called John Watson. The two start to become close until old problems start to resurface and Sherlock starts having to fight for his life.