Yu-Gi-Oh! GX: The Successor of the Dragons
Naruto Wheeler and Sayuri Kaiba, the son and daughter of Joey Wheeler and Seto Kaiba respectively, enter Duel Academy to make themselves better duelists, and to find out what happened to all the missing students. Naruto x Female Sauske. Might be Synchro Monsters in this, but I'm still deciding on that.