Emma Woodhouse, aged 20 at the start of the novel, is a young, beautiful, witty, and privileged woman in Regency England. She lives on the fictional estate of Hartfield in Surrey in the village of Highbury with her elderly widowed father, a hypochondriac who is excessively concerned for the health and safety of his loved ones. Emma's friend and only critic is the gentlemanly George Knightley, her neighbour from the adjacent estate of Donwell, and the brother of her elder sister Isabella's husband, John. As the novel opens, Emma has just attended the wedding of Miss Taylor, her best friend and former governess. Having introduced Miss Taylor to her future husband, Mr. Weston, Emma takes credit for their marriage, and decides that she rather likes matchmaking.

Sophie Allen is a Pre-Med student, a hard worker, and head over heels in love with her long-time boyfriend, Bryce Harrison. Bryce Harrison is a baseball jock, a lover of the movie Hairspray, and head over heels in love with his long-tie girlfriend, Sophie Allen. That is, until Bryce's world is turned upside down with the big-C. A cancer diagnosis. What does it mean to love someone unconditionally? And just how far would you go for the person that you love? Sophie is about to find out.