River's memory has been wiped by the Natroginies. She's a wanted criminal by a lot of people- and aliens- and her and the Doctor are forced to find out why and how to fix everything but how can they do that when River can't make the decision on whether she wants to get her memories back or not....?

Meet Sherlock Holmes- a 15 year old sociopath; arrogant, tactless, rejected, but enjoys a life of solitude and deducing. Meet John Watson- a 15 year old footballer; quiet, popular, caring, but endures a life of isolation and oppression. A transfer from a state school, John pushes open the door of Room 22 to find the most crucial part of his life he never knew existed; a teenage boy with the mind of a philosopher, who just so happens to be able to precisely analyse every detail of John's life, whilst being able to piss everyone else off at the exact same time.

What will happen when Sherlock gets a toothache?