Thanks to the efforts of the future foundation and the survivors of the killing school life, Junko Enoshima's despair has greatly weakened. But one last thing stands in the way of true hope... The ultimate despair. AKA, Hope's Peak Academy's 77th class. A solution to that issue has been put into motion, but... what will you do when somethings don't go according to plan?

Just as he and his wife Mia start getting their life back together, Ethan Winters life takes another turn for the worse when Mia is murdered and his daughter kidnapped. In order so safe her, he travels all the way to a remote village in Transylvania. There, he disocvers the origins of Umbrella as well as mutants and mythical monsters. Ethan thought he had seen everything after what happened at the Baker Farm. But he was wrong. Very wrong... Luckily for him, he soon stumbles upon an unlikely ally in this dangerous place.