The story is about an orphan, Oliver Twist, who endures a miserable existence in a workhouse and then is placed with an undertaker. He escapes and travels to London where he meets the Artful Dodger, leader of a gang of juvenile pickpockets. Naively unaware of their unlawful activities, Oliver is led to the lair of their elderly criminal trainer Fagin.

The story traces the life of David Copperfield from childhood to maturity. David was born in Blunderstone, Suffolk, near Great Yarmouth, Norfolk, England, in 1820, six months after the death of his father. David spends his early years with his mother and their housekeeper, Peggotty. When he is seven years old, his mother re-marries Edward Murdstone. David is given good reason to dislike his stepfather and has similar feelings for Murdstone's sister Jane, who moves into the house soon afterwards. Murdstone thrashes David for falling behind in his studies. Following one of these thrashings, David bites him and soon afterwards is sent away to a boarding school, Salem House, with a ruthless headmaster, Mr. Creakle. There he befriends James Steerforth and Tommy Traddles.