It started out as a regular school day, until Edd had gotten attacked in the bathroom. Ed, Edd, and Eddy run home to try and survive what is happening to the world. When they meet up with Kevin, it's never a nice meeting between them.
With the Zombie Apocalypse with no close, Double D, Kevin, RevKev, Eddy, and RevEdd have to try and keep surviving during these hard times. There has been talk of a safe haven for all kinds of people.