"Drake Palma, humanda ka! I'm going to get you by hook or by crook!" Ito si Alys Perez, may pagka-loner, maingay, madalas bagsak ang grades sa klase, bigo sa pag-ibig, at may malaki siyang problema. Kasi naman, pumayag siyang gawin ang isang bagay na wala talaga siyang kahit anong experience. Ano ba naman ang alam niya sa pangse-seduce? At lalo na sa matalino, hot na hot, at super sungit na classmate pa niyang si Drake Palma?! Ah basta! Gagamitin niya ang lahat ng powers niya para maging "mission accomplished" sa challenge na ito. Hindi siya makapapayag na maging isa sa napakaraming babae sa school na naging brokenhearted dahil sa playboy na si Drake.

The new semester opens with a bang that shocks the four Houses of QED University, an exclusive school for promising students of the science of deduction and art of detection. The Holmesian Harriet Harrison never thought that the day would come when their archnemesis Moriartian faction beat them in the House War. Her competitive attitude toward her class rival Morrie Moreno intensifies, each trying to outsmart and outmaneuver the other. But trouble does not stop there. The most charming Adlerian Aiden Alterra commits himself to a "secret mission" and starts pestering Harriet. The seemingly mute Wilhelmina Williams from the Watsonian faction also gets dragged along with the three in a string of mysterious incidents that will plague the university. Despite their dissenting motivations and unique personalities, the four will have no choice but to work together as a team toward one common goal and against one common enemy. The classes begin. Character illustrations by RAZE_DALI