In Universe 4, only the girls know about the fact that they will disappear once they fail to find and be in a relationship with their soulmates. But Rio Latino is different because she only wants one thing, and that is to disappear from the world. In an attempt to end her life, she was rescued by a boy with a similar flower tattoo as hers. That fateful encounter will change her view about life. Eager to make him notice her, she will realize it wasn't easy. After all, the boy she likes has a rose tattoo, while hers is a carnation.

In Universe 4, girls have something invisible to others, but not to those they are destined to be with. Yeji Hernan must be careful of who she falls in love with because someone among her circle of friends has a plan to stop her from knowing her soulmate. If she falls in love with the wrong person, she will disappear.

Athena Siguenza, a patient with cardiomyopathy fell for Mon Viernes, a married man whose wife was in coma for years. Showing no signs of recovery from Wendy, the wife, the two of them asked Wendy's parents to let him go. As their relationship grew deeper, Wendy woke up. Seeing how her husband fell in love with the girl she secretly hated for years, she refused to let him go and tormented Athena with it. Is it worth chasing a married man?

With the lack of affection and attention from her workaholic husband, Cana Quijares left with the intent of separating with Henesi until she finds herself again. Months of not enjoying the new life she has, she decided to return to feel the warmth she longed for. But Henesi has found his new love and he got her pregnant. Wanting to repent and ask for forgiveness, Cana babysitted her love's child. In hope that Henesi would come back to her, she realized what exactly they lost that drove them apart.

Eve Marvilla is engaged to Vermus Milandro, an extremely popular man in their town. It was a surprise to her that her playground narcissistic crush since childhood agreed to it. She was living her life happily with him when Risha Laxima, Vermus' ex-girlfriend, came back and tried to complicate things. Nevertheless, the wedding preparations continued. But it was a nightmare when Eve learned what was really going on.

The moment Hera Siguenza laid her eyes on Austin Milandro, she knew that he'll be hers. Both of them fell for each other. Their story goes with the saying, "It is much better that the other one is more in love than the other." As Hera indulge herself into his life, she learned how to love a rose the hard way.

Showbiz life has never been easy for people in the entertainment industry. Both Gab and Elle are at the peak of their careers. Elle has a crush on her fellow actor since childhood that eventually turned into love, something the public is well-known of. At home, Elle is nothing but a maid named Heliana in her step-mother's house. One night, she met Ismael, a local resident of their town. The two got close and would normally spend their afternoons with each other. Scenes after scenes, pretensions after pretensions, her love for Gab broke Ismael and Elle apart. Who is for her? Will she make the right choice in the end?

Haunted by series of blurry dreams, Rei Canseco chained his heart up for all, except for Cynthia, his the-one-that-got-away. On his journey seeking for her, he met Emma de Avila, a person that resembles Cynthia, whose dream is to travel the world. As both of them traveled in and out the country for months, Rei's dream became clear that eventually ruined the budding relationship between him and Emma.

Guila Severro had never received love from her family even if she was a well-known ballerina. After being caught in an accident, she woke up as Gaile, Herald Aleman's girlfriend. Herald is popular for his looks and job position, but is a control-freak. He loved and controlled her for years and when he had to leave, Guila was left in Arcius' care, his cousin. As the two of them bond on the country side, she finally felt free, something Herald has deprived her of. But it all ended when Herald came back and Arcius decided to leave.

What happens if feelings are burried? They grow. After secretly loving her friend for a decade, will Carmen Perez be brave enough to admit what she truly feels? Will she be able to handle consequences for loving Peter Marques?