The SCP Foundation is under the control of Knox, a leader who wields his power through fear and tyranny. The Serpent's Hand, a secret organization dedicated to freeing SCPs and persons-of-interest from his clutches, is desperate for an opportunity to make their move against him. When two brothers are revealed to be immune to SCPs, it becomes a dance with the devil as members of The Serpent's Hand race to stop Knox before he eliminates everyone in his path.

Zoe Harper, the younger sister of Roy, is 19 years old with a grisly history of crime. What do you expect from living in the Glades? One afternoon, Roy steals the purse of Thea Queen, and the Harper's lives are never the same again.