The SCP Foundation is under the control of Knox, a leader who wields his power through fear and tyranny. The Serpent's Hand, a secret organization dedicated to freeing SCPs and persons-of-interest from his clutches, is desperate for an opportunity to make their move against him. When two brothers are revealed to be immune to SCPs, it becomes a dance with the devil as members of The Serpent's Hand race to stop Knox before he eliminates everyone in his path.