Dreandra Verceluz is a sophomore engineering student, who carries the heavy responsibility of being the family's eldest child and pressure from her family and relatives' expectations. She had come to Manila to build the dreams she had ever since, but crossing paths with the university's infamous law student, Antonio Sherion Coronel, had caused her to stray from the path she planned to walk on.

Tonette Reanzares is a walking disappointment, as what her family had labeled her after she repeated a year in high school and shifting from one course to another. She finally settled her decision and took the path of being an English teacher, despite her family's objection. Her life was changed forever after meeting the frisky biology student, Peter Lucente.

Portia Zalea Angeles is an adopted daughter of a family who lives under the bridge in the poor streets of Manila. She stayed with the childless couple, who took care of her for years, only to get allegedly suspected of their murder. In the midst of horrific events in her life, she met the playboy aeronautical engineer student from the neighboring university, Clarkson Belardo.

Zoey Razon ran away from home upon knowing that her family set her marriage up with someone she doesn't even knew. Not knowing where to go and having no real friends to rely on, she wandered into the university grounds. She bumped into her professor, Leoncencio Ynares, and there asked him if she can stay under his roof.