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Viserys Targaryen II had three children, but when his wife Larra Rogare left to Lys she sent back a baby girl and a wet nurse months later.
King Aegon IV, Aemon the dragon knight, and Naerys Targaryen had one more sister, her name was Naella Targaryen, born 140 AC. When her mother Larra Rogare left to Lys in 139 AC, she had been pregnant with Naella and was sent to kingslanding months after her birth, it is said Princess Naella was the favorite sibling amongst her brothers and sister. Naella would then marry Heir Martyn Redwyne and she would have six four sons and two daughters.
This unknowingly affects the future of what would lead to a change of ripples through the future of Westeros.