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Sayomi Uchiha loved and cared for her twin, Nozomi, to the point that she would do anything for her. After obtaining the complete form of her basic Sharingan, she noticed that her older brother, Itachi, had an even greater form of the Sharingan. When she realized that her relative Shisui had died, she sought to obtain that form of the Sharingan, the Mangekyo Sharingan. She decided to lure one of her best friends into the woods. Once she did, she murdered her and got what she thought she would, that advanced form of the Sharingan. She made sure to make her beloved friends body unfindable, so that suspicion would not lead to her. Sayomi had no idea what the consequences of using the Mangekyo Sharingan too much was, so she used it over and over until she felt herself going blind. After she became a Chunin, she took her sister Nozomi into the woods to play before she got her first mission as a military leader. When she arrived, she saw Sasuke on his knees and that the whole clan was murdered except for Sasuke, Nozomi, and Sayomi. Sayomi took her younger sister inside the house and cared for her. Every time Sayomi went on missions, she ended up using her Mangekyo Sharingan through habit. After about a year of going on these missions, she noticed that if she used her Sharingan once more, she would go completely blind. When she went into Nozomi's room to tuck her in for the night, she got an idea. If she were to take her sister's eyes then she would be able to see for a little longer, or at least she thought. The only thing that was different from what she thought was that if she stole her sister's eyes, she would never have to worry about losing her eyesight again. Sayomi took her sister's eyes and used them to regain her complete eyesight back. Later on, she successfully became a jounin, causing Danzo to take interest in her Sharingan.