Dani has severe Tourette's syndrome, Jenner has congenital heart disease, Zara has cancer, Adebiyi severe schizophrenia, Calla is anorexic, Ezra is bulimic and has bipolar disorder, Kristofer has cystic fibrosis, and they are all in Roxanne Defier Pediatric Hospital. They are all patients. All different sicknesses. But at least they know theirs. Isabella has had a rough couple of days so when she's admitted into the hospital she thinks it will finally end. It doesn't. No one knows what's wrong with her she has symptoms for a number of diseases but then some don't fit that disease. They try to help the best they can but its not going to well. So when she meets Jenner, Ade, Dani, and Ezra life seems to get a whole lot better.