Following the fall of the Institute, much of Nate's Commonwealth has flourished. Robots, traders, and wastelanders of all creeds find themselves drawn to the potential for new horizons. Unfortunately, not everyone can be trusted as whispers of the Railroad still linger, amidst the divided territory of the daring Boston Brotherhood and local heroes, the Minutemen. Set three years after Nate's victory, old friends and new ones begin to unravel the brewing dangers.