Being a superhero sometimes means you forget about the small dangers in the world, like disease. For Peter, this means he loses May to natural causes, not something he could ever save her from.
Unknown to him, May left custody of Peter in the hands of Tony Stark, who, even though he wants kids, has no idea how to actually raise one. With a grieving superhero teenager on his hands, Tony is going to have to figure it out quick, if he wants Peter to ever be able to move on and be happy.
In an Alternate Universe where Mr. Tony Stark survived the final battle with Thanos, he was tossing and turning one night as he feels like he should have done more... or could do more. He comes up with the brilliant idea of creating a new group of Avengers but with young blood. Of course what is it without Peter Parker to be one of the first students he recruits. Tony brings in many young heroes to get the proper training that they need to be an Avenger. One student though catches the young web slinger's heart. Will she be his one and only or will she be the death of him? Only time will tell when you spend time at the Avengers Academy.