Joanna is just starting her grade ten year of high school, when she meets a boy- Will. He is new to the school and his attentions is quickly captured by Joanna's presence. But when they two start to hit it off, something terrible happens. Joanna is diagnose with a disease. Meanwhile, the world is changing. Horrible things are happening all around the world, jeopardizing human existence.Will, Joanna, and their friends have to fight to survive and keep Joanna's condition stable at the same time. Will Joanna and Will make it through these events? What will happen to the world as we know it? Who will live and who will die?