It's been several months since Homecoming, and the Midtown Halloween Spooktacular is nearing. Peter wants to go with Ned like every other year, but he's been grounded ever since May found out about his secret life as Spider-Man. To make things worse, she's forbade him from fighting any and all crime, claiming it's too dangerous and that he's got better things to worry about like school. What May doesn't know is that he's been sneaking out every night to fight only the smallest of crimes, not wanting to get into any real trouble. Unfortunately for Peter, trouble finds him when a blood-sucking creature of the night begins to run rampant throughout the city. Things get even more complicated when our hero realizes he isn't the only one thats after the bloodthirsty monster...