Natalie Johnson is the best oncologist in New Orleans. But despite her success of being a physician, she has a very traumatizing past that she'd prefer not to talk about. Ethan Sloan is a renounced neurosurgeon in the entire state. But he is living his life with a very heavy weight on his shoulders. But in the world of medicine, the field is small. So when the two bumped into each other for the second time, will their past dictate the desires they feel for each other?