Spider-Man: Far From Love

This story takes place during spiderman far from home. Serenity Winchester, daughter of Sam Winchester, is assigned a mission from Nick Fury to kill the elementals in Europe. But when Sam and Dean find out what she's been up to they forbid her from going. Serenity being the person she is disobeys her Dad and Uncle.

As for Peter Parker who will be going to Europe for a school trip, meets Serenity while she was in NYC hunting ghost. The two really hit it off, well until Serenity decides to tell Peter who she is and everything goes downhill for them.

A couple weeks later it's time for Serenity to start off on her mission and for Peter to go on his trip. Will Peter and Serenity find their way back to each other or will others get in the way.
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This is like a crossover with the show supernatural and Spider-Man far from home. You don't have to watch the show to understand anything since the story's mainly focused on the Spider-Man side of things, and Sam and Dean will only be in the book for the 1st and last chapter!