This is set in the Uncharted universe. Which means, no huntsmen or huntresses, no grimm, no Salem, no maidens, etc. In this case, if there's no grimm, Salem, no faunus' (means Blake and every other faunus is human), and hunters and huntresses. That means that Summer doesn't die, Adam can't lead the White Fang cause it doesn't exist and no need to exist (well, not for the exact same reason, hint; foreshadowing future parts), etc. Some things are the same, but a little different. Examples are that Roman Torchwick is a criminal and thief but doesn't steal dust, Weiss family does own a company but doesn't manufacture dust (don't know what yet), Raven is still a leader of bandits (or something similar, maybe modern day pirates), Qrow still gets drunk (no changes to that at all), etc.