SILAC service
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Ongoing, First published Oct 16, 2019
SILAC relies on metabolic incorporation of a given 'light' or 'heavy' form of the amino acid into two samples. As the two isotopically labeled amino acids are essentially chemically identical, their incorporation does not interfere with normal cell growth, while leading to proteins/peptides that are distinguishable by mass and thus are ideal for mass spectrometric analysis.
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