Waking up on the USG Ishimura, unsure of what has happened you were saved by Isaac Clarke from being killed. After he filled you in on what as happened you both fought through the outbreak, and got out alive. But three years later both you and Isaac couldn't remember how you got to Titan station, but another outbreak has occurred, and for a second time you and Isaac was forced to stop it unknowingly that you both, and Nolan Stross had made a marker. After getting through and meeting Ellie Langford we both got to the end, and sent Ellie on a ship away we both confronted Tidemann, and when we did we both sat down waiting for the end.