Operation Manimals

In 2048, A woman named Reginae Mack, who had fallen from grace due to increasing isolating herself from her peers, press, and family due to the aftermath of tragedy, creates the first "manimal", as part of a project designed for manual labor in a modern environment, and also is a landmark by being the first man-made species. However, 4 of the experiments made unintentionally gain sentience, and in 2060, escape from captivity into the urban world, struggling until a few people take them in.