Dave and Jo are not your typical childhood sweethearts who grew up together from the moment they were born. Met in high school and got closer from there, these two find themselves more inseparable than Siamese twins. But, what happens when one of them gets news that may change their plans for their future together? And what happens when another starts to feel things that may not be that platonic? BOOM! Add in a little humor and some meddling from life, watch how Dave and Jo try to keep hold on their friendship. Can they last?