Coming from a conglomerate family, Dr. Kang Hanna has dreams different from her family's - to be a neurosurgeon. She has always struggled to prove to them they didn't make the wrong choice of letting her pursue her own happiness. Dr. Kim Seonho, is the first and only son of a family of doctors and is set to inherit Yangju Medical Center. Like Hanna, his dreams are different from his family's - to be an actor. Graduating at the top his class didn't make him realize his passion for this profession because his heart has always wanted to do something else. What will happen if Hanna, the clever neurosurgeon whose only one rule in dating is to never date doctors, meets Seonho, the mischievous pediatric surgeon whose rule is different from hers?