Elizabeth Byers has been to Hell and back. As the last surviving member of an ancient race known as the Time Lords, Elizabeth is determined to start her life over on Earth after she loses her entire family, species, and planet during the last days of an infamous conflict known as the Time War. Now settling back on Earth, Elizabeth is accepted into a surgical residency program at Seattle Grace Hospital, where she quickly realizes that there is much more to being a doctor than just taking care of patients.