Sam Winchester and his brother, Dean, lost their mother twenty-four years ago in a supernatural murder. Now, they criss-cross the country, hunting monsters, demons, and ghosts. One day, they stumble upon a case in Yellowstone National Park. Something is wrong with the animals. The brothers reluctantly check the case out and take it, but it proves to be more difficult than they previously expected. On top of this, Sam meets a young woman in the forest. She claims to be a hunter and she knows what's happening in Yellowstone, but little do the brothers know there is more to her than meets the eye...