Dean and Sam attend Supernatural High, a high school for all things Supernatural. Along the way, they meet a bunch of colorful characters including the nerdy angel in a trench coat, Castiel, a trickster named Gabriel, and Crowley, the king of the school, who apparently is out to ruin Castiel. Meanwhile, Adam Milligan is struggling with the new feelings he harbors for Michael, the archangel. And Lucifer, who is trying to repair his relationship with Michael and keep his demonic girlfriend satisfied, is not pleased when he discovers his brothers' feelings for the Winchester boys. And just when things reach what everyone thinks is the epitome of their conflict, a new, darker, and deadlier foe appears on the horizon. Those who were once enemies must put aside their differences and stand together against this new villain who may or may not have ties to our heroes.