Pokemon: No Way Home

Ash is betrayed by his mother, Professor Oak, and some of his friends after the Alternate Worlds fiasco. When he refuses to give up his dreams, they end up killing Pikachu, who reprimands them, by accident. Before Ash can go down a dark path, strange things begin happening. Ash and everyone else are suddenly the ages they are canonically supposed to be, Cyrus is still alive and has apparently been manipulating things, brings from other universes are loose in the world, Ash has multiple girlfriends... Just when Ash thought his life couldn't get any weirder. Ash x Harem.